For the project titled “Rational combination therapies with lenvatinib for advanced thyroid cancer.” This grant is the Ric Blake Memorial Thyroid Cancer Research Grant. This project aims to develop rational drug combinations with lenvatinib to further improve the efficacy of systemic treatment for advanced progressivethyroid cancer. This multidisciplinary project combines functional genomics, high-throughput pharmacology, and bioinformatics to identify drugs and drug targets that will have synergistic anti-proliferative effects in combination with lenvatinib on thyroid cancer cells. Dr. Pozdeyev is on the staff of the Department of Medicine at the University of Colorado. His research focuses on the study of pharmacogenomics relationships in thyroid cancer and the development of rational combination therapies for progressive metastatic thyroid cancer. A graduate of Saint Petersburg Pavlov State Medical University in Russia, he completed internship and residency programs at MedStar Harbor Hospital Center in Maryland, and a fellowship at the University of Colorado.